教师简介

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高兰昌

2022年02月28日 09:31  点击:[]

一、个人基本情况

高兰昌,男,汉族,生于1984年10月,中共党员。2021年6月毕业于华中科技大学生物医学工程专业,获得工学博士学位;2013年6月毕业于中南民族大学高分子化学与物理专业,获得理学硕士。2013.7-2014.9与中南民族大学化学与材料科学学院工作,实验员。2010年6月毕业于中南民族大学应用化学专业,获得理学学士学位。

主要研究兴趣和方向:(1)中枢神经药物(精神病药物、麻醉、镇痛)的设计、合成及活性评价。(2)光催化在绿色有机合成中的应用和光催化对环境有机污染物消除的研究。

二、研究论文

1.Gao,L.,* Hao C, * Ma, R., Chen, J., Zhang, G., Chen, Y. Synthesis and Biological Evaluation of a New Class of Multi-target Heterocycle Piperazine Derivatives as Potential Antipsychotics.RSC Advances,2021, 11: 16931–16941.(共一作)

2.Gao,L., Hao, C., Chen, J., Ma, R., Zheng, L., Wu, Q., Liu, X., Liu, B. F., Zhang, G., Chen, Y., Jin, J..Discovery of a new class ofmulti-targetheterocyclePiperidine derivatives as potential antipsychotics with pro-cognitive effect,Bioorganic & Medicinal Chemistry Letters,2021, 40:127909.

3.Gao, L.,* Yang, Z.,* Xiong, J., Hao, C., Ma, R., Liu, X., Liu, B. F., Jin, J., Zhang, G., Chen, Y.. Design, synthesis and biological investigation of flavone derivatives as potential multi-receptor atypical antipsychotics,Molecules,2020, 25(18): 4107.(共一作)

4. Huang, L.,Gao, L.,* Zhang, X., Yin, L., Hu, J., Song, T., Chen, Y. Synthesis and pharmacological evaluation of piperidine (piperazine)-amide substituted derivatives as multi-target antipsychotics.Bioorganic & Medicinal Chemistry Letters,2020, 30(20): 127506.(共一作)

5. Yang, C.,*Gao, L.,* Zhang, B., Zhang, Z., Deng, K. Uniform zinc thioporphyrazinenanosphere by self-assembly and the photocatalytic performance.Journal of Porphyrins and Phthalocyanines,2018, 22: 1-9.(共一作)

6.Gao, L., Deng, K., Zheng, J., Liu, B., Zhang, Z. Efficient oxidation of biomass derived 5-hydroxymethylfurfural into 2,5-furandicarboxylic acid catalyzed by merrifield resin supported cobalt porphyrin.Chemical Engineering Journal,2015, 270: 444-449.

7.Gao, L., Liu, B., Zhang, Z., Huang, K., Hu, X., Deng, K. Efficient synthesis of n-substituted pyrrolescatalyzed by a novel an organic–inorganic hybrid solid acid catalyst.Journal of Organometallic Chemistry,2014, 44(41): 26-31,

8.Xiong, J., Jin, J.,Gao, L., Hao, C., Liu, X., Liu, B. F., Chen, Y., Zhang, G.Piperidinepropionamide as a scaffold for potent sigma-1 receptor antagonists and mu opioid receptor agonists for treating neuropathic pain.European Journal of Medicinal Chemistry,2020, 191:112144.